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Botox injections may be critical to cutting cancer growth
By Helen Andrews 21 Aug 2014
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”


News
1 to 12 of 8704 news stories
25 Apr 2024
Kerzner International has signed deals to operate two new Siro recovery hotels in Mexico and Saudi Arabia, following the launch of the inaugural Siro property in Dubai this February. Designed to offer guests a holistic ... More
24 Apr 2024
The US spa industry is continuing its upward trajectory, achieving an unprecedented milestone with a record-breaking revenue of US$21.3 billion in 2023, surpassing the previous high of US$20.1 billion in 2022. This data stems from ... More
24 Apr 2024
Short-term incentives to exercise, such as using daily reminders, rewards or games, can lead to sustained increases in activity, according to new research. Researchers found that even a simple daily reminder encouraged people to move ... More
24 Apr 2024
Spa and wellness veteran Shannon Malave has been named spa director at iconic US spa destination Mohonk Mountain House. Based in New York’s verdant Hudson Valley and founded in 1869, Mohonk is a historic Victorian ... More
23 Apr 2024
Six Senses Kyoto opens its doors today, marking the eco-luxury hotel and spa operator’s entry into Japan and a new addition to its urban collection. Situated in the historic Higashiyama district, the 81-key hotel is ... More
23 Apr 2024
The UAE’s first-ever Dior Spa has officially launched at The Lana, Dubai – the Dorchester Collection’s debut property in the Middle East. Bathed in natural daylight on the hotel’s 29th floor, Dior Spa The Lana ... More
22 Apr 2024
The Sacred River Spa at Four Seasons Resort Bali at Sayan will reopen later this year with an all-new design plus enhanced treatments and experiences inspired by its river valley home. Nestled amid rich tropical ... More
18 Apr 2024
The Global Wellness Institute (GWI) has released new data on the US’ wellness economy, valuing it at US$1.8 trillion. According to the organisation's recent report – called The Global Wellness Economy: United States – the ... More
19 Apr 2024
UK sauna enthusiasts will converge at Galgorm Resort in Northern Ireland next week for the highly anticipated second annual UK Aufguss Championships. Hosted from 22-24, the event will see competitors from across the UK showcasing ... More
17 Apr 2024
Remedy Place, a US-based social wellness club brand, is poised for steady expansion in the coming years, with plans to open two new clubs annually moving forward Remedy Place is the brainchild of Dr Jonathan ... More
16 Apr 2024
Swiss longevity brand Clinique La Prairie (CLP) has inked a deal with Montara Hospitality Group to operate a resort at Tri Vananda – a purpose-built wellness community in Phuket, Thailand. Tri Vananda, envisioned as a ... More
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Six Senses has announced the grand opening of its first-ever property and spa in the Caribbean, called Six Senses La Sagesse. With a picturesque beachfront setting and surrounded by verdant hills, Six Senses La Sagesse ... More
     
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Spa Life International
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NEWS
Botox injections may be critical to cutting cancer growth
POSTED 21 Aug 2014 . BY Helen Andrews
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”
RELATED STORIES
Study to explore anti-inflammation effects of yoga on cancer patients


A study will begin in the US this December to test the effectiveness of yoga in tackling the inflammation commonly suffered by cancer patients, caused either by tumours or treatments.
Spafinder and cancer education organisation form partnership


Spa and wellness media and marketing company Spafinder Wellness has partnered with non-profit cancer-focused education organisation Wellness for Cancer.
Botox may stunt emotional growth in young people: study


Botox injections that induce temporary paralysis of muscles in the upper face – to reduce wrinkling when people frown – could stop young people seeking this treatment from learning how to express emotions fully, according to a study.
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Kerzner to expand Siro portfolio with recovery-focused hotels in Los Cabos and Riyadh
Kerzner International has signed deals to operate two new Siro recovery hotels in Mexico and Saudi Arabia, following the launch of the inaugural Siro property in Dubai this February.
US spa industry hits record-breaking US$21.3 billion in revenue in 2023
The US spa industry is continuing its upward trajectory, achieving an unprecedented milestone with a record-breaking revenue of US$21.3 billion in 2023, surpassing the previous high of US$20.1 billion in 2022.
Immediate rewards can motivate people to exercise, finds new research
Short-term incentives for exercise, such as using daily reminders, rewards or games, can lead to sustained increases in activity according to new research.
Shannon Malave appointed spa director at Mohonk Mountain House
Spa and wellness veteran Shannon Malave has been named spa director at iconic US spa destination Mohonk Mountain House.
Six Senses unveils urban wellness retreat in Kyoto inspired by Japanese Zen culture
Six Senses Kyoto opens its doors today, marking the eco-luxury hotel and spa operator’s entry into Japan and a new addition to its urban collection.
US named world’s largest wellness economy, reaching US$1.8 trillion valuation
The Global Wellness Institute (GWI) has released new data on the US’ wellness economy, valuing it at US$1.8 trillion.
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COMPANY PROFILES
Phytomer

Phytomer remains an independent family business led by the founder’s son, Antoine Gédouin. We coun [more...]
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23-25 Apr 2024

ISPA Conference 2024

Phoenix Convention Center, Phoenix, United States
28-30 Apr 2024

Spa Life Scotland

Radisson Blu Hotel, Glasgow,
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