23-25 Apr 2024
Phoenix Convention Center,
Phoenix,
United States
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28-30 Apr 2024
Radisson Blu Hotel,
Glasgow,
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08-08 May 2024
Hotel Melià ,
Milano ,
Italy
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10-12 May 2024
China Import & Export Fair Complex,
Guangzhou,
China
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13-16 May 2024
Conrad Chia Laguna Sardinia ,
Italy
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14 May 2024
JPMorgan Chase Headquarters,
New York City,
United States
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18-22 May 2024
The Ravenala Attitude Hotel,
Mauritius
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23-24 May 2024
Large Hall of the Chamber of Commerce (Erbprinzenpalais),
Wiesbaden,
Germany
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Could exercise be used to treat breast cancer? |
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By Kath Hudson 07 Apr 2015 |
Exercise could potentially become a treatment for breast cancer
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Exercise can slow the growth of breast cancer tumours in mice, according to research published in the Journal of the National Cancer Institute.
One way that cancers grow resistant to treatment is by generating a jumbled web of blood vessels which stop oxygen getting to the tumour. When starved of oxygen, the tumour is protected from chemotherapy drugs and radiation, as these treatments are designed to seek out well-oxygenated tissue.
Researchers have tried many different approaches to improve blood flow to tumours, but exercise has proved to be the most promising by far.
“We could not have guessed it would be as effective as it was,” says co-senior author, Mark W Dewhirst. “I have spent the better part of the last 30 years trying to figure out how to eliminate hypoxia in tumours and have looked at a lot of different approaches: drugs, hyperthermia and metabolic manipulations. None has worked very well, and in some cases, made things worse. So these findings with exercise are quite encouraging.”
The researchers used two different models of breast cancer cells and implanted them in mice and then assigned the animals to exercise (running on a wheel), or remaining sedentary.
Tumour growth was significantly slower in animals that exercised than sedentary mice and tumour cell death was 1.5 times higher.
Researchers also tested if exercise would improve the efficacy of the chemotherapy drug, cyclophosphamide. Animals were randomised into four groups: sedentary, exercise alone, cyclophosphamide alone and exercise and cyclophosphamide.
The rate of tumour growth was significantly lower in mice treated with exercise and cyclophosphamide, compared to other groups.
Also significant, tumour growth was delayed in both the exercise alone and cyclophosphamide alone groups, with no difference in the tumour growth rate suggesting that, in this study, exercise was as effective as chemotherapy.
On the basis of these findings, studies are being designed to test whether exercise can inhibit tumour growth and the risk of recurrence in humans.
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News |
1 to 12 of 8703 news stories |
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24 Apr 2024
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24 Apr 2024
Short-term incentives to exercise, such as using daily reminders, rewards or games, can lead to sustained increases in activity, according to new research. Researchers found that even a simple daily reminder encouraged people to move ... More
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24 Apr 2024
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23 Apr 2024
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23 Apr 2024
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22 Apr 2024
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18 Apr 2024
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19 Apr 2024
UK sauna enthusiasts will converge at Galgorm Resort in Northern Ireland next week for the highly anticipated second annual UK Aufguss Championships. Hosted from 22-24, the event will see competitors from across the UK showcasing ... More
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17 Apr 2024
Remedy Place, a US-based social wellness club brand, is poised for steady expansion in the coming years, with plans to open two new clubs annually moving forward Remedy Place is the brainchild of Dr Jonathan ... More
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16 Apr 2024
Swiss longevity brand Clinique La Prairie (CLP) has inked a deal with Montara Hospitality Group to operate a resort at Tri Vananda – a purpose-built wellness community in Phuket, Thailand. Tri Vananda, envisioned as a ... More
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15 Apr 2024
Six Senses has announced the grand opening of its first-ever property and spa in the Caribbean, called Six Senses La Sagesse. With a picturesque beachfront setting and surrounded by verdant hills, Six Senses La Sagesse ... More
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12 Apr 2024
A brand new desert hot springs oasis, called Zion Canyon Hot Springs, is set to open in Southern Utah in Q3 of 2025. Situated 30 minutes from the majestic Zion National Park, the US$60 million ... More
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BC Softwear Ltd |
British-based, BC SoftWear was launched in 2002 by founder and managing director, Barbara Cooke.
[more] |
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