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Mayo Clinic study unlocks new anti-ageing science
By Megan Whitby 19 Sep 2019
The Mayo Clinic's findings represent hope for a future systemic solution to ageing and age-related diseases.
New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.


News
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03 Apr 2020
Airport spa operator XpresSpa is joining the efforts to combat coronavirus by offering its airport locations to the US government as testing facilities. XpresSpa is an airport spa service offering express nail, massage and hair ... More
03 Apr 2020
After seven years and a £300m investment, super-boutique hotel, The Londoner, is taking shape in the heart of the UK’s capital city. Originally scheduled for June 2020, the opening has been shifted to late 2020 ... More
02 Apr 2020
Six Senses is launching a content portal to help consumers remain solution-oriented, by supporting their physical and mental wellbeing and resilience during the coronavirus shutdown. The service will be available to everyone, whether or not ... More
02 Apr 2020
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31 Mar 2020
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27 Mar 2020
The Tom Dixon-designed agua London spa has launched a new treatment menu drawing inspiration from British wild plants and hedgerows and the remedies that can be made from them. Five of agua London’s signature treatments ... More
26 Mar 2020
Holistic medical wellness resort The Farm at San Benito, Philippines, is offering an immune system strengthening programme designed to protect the body’s cells and enable them to fight infection. Since it opened in 2002, the ... More
26 Mar 2020
German skincare brand Babor has announced it has reached climate neutrality. The brand uses green electricity, photovoltaics, and climate-neutral renewable natural gas, production at its headquarters in Aachen, Germany, which has been carbon-neutral since 2014. ... More
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Deepak Chopra’s wellness company – Chopra – has partnered with The Well to unite people in a call to action to stay home and have hope through a free live-streamed global meditation event called H(om)e. ... More
     
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Jobs   News   Products   Magazine
NEWS
Mayo Clinic study unlocks new anti-ageing science
POSTED 19 Sep 2019 . BY Megan Whitby
The Mayo Clinic's findings represent hope for a future systemic solution to ageing and age-related diseases.
New science has revealed a potential solution to age-related diseases which works on a systemic basis, improving overall health and reducing the need to treat individual, age-related ailments.

A human trial in the field of senolytics – medicines which remove aged, toxic cells from our bodies – has found these treatments can decrease and potentially eliminate the presence of senescent cells in the body.

These cells are responsible for fuelling age-related diseases, as they've ceased to divide and go on to accumulate in the body, eventually becoming harmful to the tissues around them.

Cells with senescent properties are linked to the occurrence of age-related diseases and have been found in the affected tissues of people with Alzheimer’s, pulmonary fibrosis and osteoarthritis. Senescent cells are also found in people suffering from obesity.

The trial, published by The Lancet in the EBioMedicine Journal on September 18th, was conducted at the Mayo Clinic in Minnesota.

During the study, nine subjects, aged between 50-80 years and receiving diabetes therapy, were administered with senolytic drugs for three days.

Scientists concluded that ‘interventions (in this instance, the administration of senolytic drugs) targeting fundamental ageing processes such as cellular senescence could delay, prevent, or alleviate multiple age-related diseases’ in humans.

The trial findings represent hope for a future systemic solution to ageing and age-related diseases, instead of treating singular diseases one-by-one.

The research was conducted by a team led by James Kirkland, MD, PhD, with Nathan LeBrasseur, PhD, MS, and Tamara Tchkonia, PhD, who all collaborate with the Mayo Clinic.

Other recent research proved that Fisetin, a fruit-based flavonoid, is a potent senolytic which can extend health and lifespan. The substance is found in strawberries, apples, grapes and kiwi fruit.
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