10-12 May 2024
China Import & Export Fair Complex,
Guangzhou,
China
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13-16 May 2024
Conrad Chia Laguna Sardinia ,
Italy
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14 May 2024
JPMorgan Chase Headquarters,
New York City,
United States
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18-22 May 2024
The Ravenala Attitude Hotel,
Mauritius
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23-24 May 2024
Large Hall of the Chamber of Commerce (Erbprinzenpalais),
Wiesbaden,
Germany
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30-30 May 2024
Four Seasons Hotel George V,
Paris,
France
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30 May - 02 Jun 2024
Rimini Exhibition Center,
Rimini,
Italy
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06-07 Jun 2024
Sataman Viilu ,
Jyväskylä,
Finland
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Obesity is a biologically mediated disease, says report |
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By Kath Hudson 13 Mar 2015 |
Obesity is biologically mediated disease, says report
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Obesity is a disease which cannot be reliably prevented or cured with current frontline methods, according to a feature published in The Lancet.
Going forward, lifestyle change combined with bariatric surgery or weight loss drugs might be the only way to treat obesity.
The issue is that once someone is obese, biological adaptations occur, including increased fat storage capacity, which makes losing weight difficult and maintaining weight loss even harder.
Body weight seems to become biologically stamped in and defended, so the body will try to make compensatory adaptations to maintain the highest lifetime bodyweight.
The biological pressure to restore bodyweight to the highest sustained lifetime level gets stronger as weight loss increases, making it almost impossible to recover from obesity. Those that do attain a healthy bodyweight via diet and exercise have obesity in remission, according to the report.
Because of this, someone who was obese but lost weight will have to ingest 300 calories less (or burn off 300 calories more) than someone of the same weight who was never obese, just to maintain the same weight.
Because obesity is largely a biologically mediated disease, more biologically based interventions are needed, alongside lifestyle and behavioural change argues the report. Also a strategy is vital to maintain weight loss.
Biologically based interventions are anti-obesity drugs, bariatric surgery and more recently, intra-abdominal vagal nerve blockade, which uses an implanted pacemaker-like device to intermittently block signalling in the gut-brain axis via the abdomina vagus nerve, this alters the neural or hormonal signalling associated with appetite to reduce hunger and calorific intake.
It is also vital that those who are overweight should be prevented from becoming obese, as the biological adaptations which preserve the highest lifetime bodyweight do not seem to occur until obesity is sustained.
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10 May 2024
The Ritz-Carlton Reynolds, Lake Oconee in the southeastern US state of Georgia is celebrating a new milestone after unveiling its newly renovated 27,000sq ft destination spa. The vision behind the refresh was to create a ... More
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09 May 2024
Art’otel, Radisson’s contemporary art-inspired lifestyle hotel brand, has strengthened its presence in London with a new hotel in Hoxton fusing art, design and hospitality. The location features 357 art-inspired guest bedrooms and suites all with ... More
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08 May 2024
HoloBike, a holographic training bike that simulates trail rides in lifelike 3D, is aiming to push indoor cycling technology up a gear. A California-based group of engineers and designers, Saga Holographic, have been working on ... More
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08 May 2024
Luxury hotel brand Aman, widely known for its strong spa focus, has just launched its much-talked-about sister brand Janu in Tokyo – complete with a 4,000sq m urban wellness retreat. Janu Tokyo is only the ... More
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07 May 2024
Equinox, has teamed up with health platform, Function Health, to offer 100 comprehensive laboratory tests, giving members vital insights into their internal health as part of an Optimize by Equinox membership. Priced at US$40,000 a ... More
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07 May 2024
Spanish wellness brand SHA Wellness Clinic is busy preparing to bolster its wellness portfolio in 2026 with a hyper-exclusive island wellness enclave in AlJurf, UAE. SHA Emirates Island at AlJurf – created by Abu Dhabi-based ... More
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03 May 2024
The historic Breakers Hotel in Long Beach, California, is set to reopen in mid-2024 as a Fairmont Hotels & Resorts property after a significant restoration and redevelopment project. The project, initially unveiled in 2022 by ... More
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03 May 2024
High-end five-star hotel company Kempinski Hotels is making its mark in Vietnam with a luxury waterfront property overlooking the Saigon River. Set to open by 2026, Kempinski Saigon River – designed by Kengo Kuma & ... More
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01 May 2024
Marriott International has signed a new deal with Neom to open a Ritz-Carlton Reserve property as part of Trojena, a brand new year-round mountain adventure destination in Saudi Arabia. Launching in 2026, Trojena is a ... More
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27 Apr 2024
The Bannatyne Group says it has officially bounced back from the pandemic, with both turnover and profits restored to pre-2020 levels in 2023, according to its year-end results. Owned by former BBC Dragon’s Den investor, ... More
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25 Apr 2024
Kerzner International has signed deals to operate two new Siro recovery hotels in Mexico and Saudi Arabia, following the launch of the inaugural Siro property in Dubai this February. Designed to offer guests a holistic ... More
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24 Apr 2024
The US spa industry is continuing its upward trajectory, achieving an unprecedented milestone with a record-breaking revenue of US$21.3 billion in 2023, surpassing the previous high of US$20.1 billion in 2022. This data stems from ... More
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