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Botox injections may be critical to cutting cancer growth
By Helen Andrews 21 Aug 2014
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”


News
1 to 12 of 8523 news stories
03 Oct 2023
Vladi Kovanic has been recognised for her services to the spa, wellness and hospitality industries by Spa-A Federation during its 21st-anniversary gala in Paris, France. The French industry body recognised the VK-Organisation founder by awarding ... More
03 Oct 2023
A new Miraval Resorts & Spas wellness destination has opened in San Diego, California, within the Park Hyatt Aviara Resort, Golf Club & Spa. The 15,000sq ft Miraval Life in Balance Spa Aviara represents the ... More
30 Sep 2023
More than 100 people from across the academic and sport and physical activity sectors gathered at the Royal Society of Arts in London on 28 September to launch the Physical Literacy Consensus Statement for England. ... More
27 Sep 2023
Architect and designer Alberto Apostoli has unveiled his new integrated wellness consulting firm, Armonia, to bolster spas around the world and transform them into commercially and economically successful destinations. Serving as the company’s project lead ... More
28 Sep 2023
The share price of Peloton has jumped after it signed a deal to become the exclusive digital fitness content provider for athletic apparel giant, Lululemon. The five-year strategic partnership will see Peloton’s content being made ... More
27 Sep 2023
Austria-based medical wellness resort operator Lanserhof Group has announced plans to open a new health destination near Marbella in Spain. The property will mark Lanserhof’s fourth European resort and join its portfolio of destinations located ... More
26 Sep 2023
US massage franchise Hand & Stone Massage and Facial Spa is set to convert 23 Massage Green franchise locations across the US to its brand. Launched in 2004, Hand & Stone now has almost 600 ... More
26 Sep 2023
Disruptions in the way the human brain links memory and appetite could help explain some disorders associated with obesity. Research from the Perelman School of Medicine at the University of Pennsylvania, US, suggests that disrupted ... More
26 Sep 2023
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22 Sep 2023
Therme Group has received planning permission to build the UK’s first city-based wellbeing resort, Therme Manchester, after a four-year journey. Planning approval has been granted for the UK’s first city-based wellbeing resort, Therme Manchester, in ... More
21 Sep 2023
Improved mental health is now a stronger motivation for Brits to exercise than staying in shape. More than half of respondents (54 per cent) to a survey of 2,271 people – commissioned by UK Active ... More
20 Sep 2023
The World Health Organization (WHO) has published its first-ever report on the "devastating global impact" of high blood pressure, along with recommendations on the ways to win the race against the condition. The report, called ... More
     
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Jobs    News   Products   Magazine
NEWS
Botox injections may be critical to cutting cancer growth
POSTED 21 Aug 2014 . BY Helen Andrews
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”
RELATED STORIES
Study to explore anti-inflammation effects of yoga on cancer patients


A study will begin in the US this December to test the effectiveness of yoga in tackling the inflammation commonly suffered by cancer patients, caused either by tumours or treatments.
Spafinder and cancer education organisation form partnership


Spa and wellness media and marketing company Spafinder Wellness has partnered with non-profit cancer-focused education organisation Wellness for Cancer.
Botox may stunt emotional growth in young people: study


Botox injections that induce temporary paralysis of muscles in the upper face – to reduce wrinkling when people frown – could stop young people seeking this treatment from learning how to express emotions fully, according to a study.
MORE NEWS
Vladi Kovanic crowned winner of Spa-A’s 2023 Personality of the Year award
Vladi Kovanic has been recognised for her services to the spa, wellness and hospitality industries by Spa-A Federation during its 21st-anniversary gala in Paris, France.
Miraval’s fourth Life in Balance Spa opens in California at Park Hyatt Aviara Resort
A new Miraval Resorts & Spas wellness destination has opened in San Diego, California, within the Park Hyatt Aviara Resort, Golf Club & Spa.
Physical literacy initiative will ‘build a nation that loves to move’
More than 100 people from across the academic and sport and physical activity sectors gathered at the Royal Society of Arts in London on 28 September to launch the Physical Literacy Consensus Statement for England.
Alberto Apostoli spearheads launch of Armonia wellness consultancy
Architect and designer Alberto Apostoli has unveiled his new integrated wellness consulting firm, Armonia, to bolster spas around the world and transform them into commercially and economically successful destinations.
Lululemon dumps Mirror and signs up with Peloton for digital content – shares jump on the news
The share price of Peloton has jumped after it signed a deal to become the exclusive digital fitness content provider for athletic apparel giant, Lululemon.
Lanserhof to enter Spanish market in 2026 with Marbella health resort
Austria-based medical wellness resort operator Lanserhof Group has announced plans to open a new health destination near Marbella in Spain.
+ More news   
 
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Living Earth Crafts

For 50 years, LEC has been manufacturing award-winning spa equipment for the world’s finest spas an [more...]
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04-06 Oct 2023

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