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Botox injections may be critical to cutting cancer growth
By Helen Andrews 21 Aug 2014
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”


News
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Spa Life UK
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News   Products   Magazine
NEWS
Botox injections may be critical to cutting cancer growth
POSTED 21 Aug 2014 . BY Helen Andrews
Probing the inner workings of cancer can spark ideas for innovative new treatments Credit: Shutterstock / Poznyakov
Botox injections, usually used in the fight against ageing, may help battle cancer, according to data from medical trials performed on mice – published in Science Translational Medicine.

Scientists from Columbia University Medical Centre, New York, and the Norwegian University of Science and Technology in Trondheim found that using the Botulinum toxin – the neurotoxin that disrupts nerve function to relax muscles and even out wrinkles when applied to tissue under the skin – could halt the growth of stomach tumours when applied to the vagus nerve, which runs from the brain to the digestive system.

A growing body of work suggests nerves help fuel cancer growth, according to the BBC. Therefore when botox is used to kill the nerves – or if the nerves are severed – tumour growth rates slow and they become more vulnerable to chemotherapy.

“If you just cut nerves is it going to cure cancer? Probably not,” said one of the researchers Dr Timothy Wang. “At least in the early phase, if you [disrupt the nerve] the tumour becomes much more responsive to chemotherapy – so we don’t see this as a single cure, but making current and future treatments more effective.”

Some trials have begun in people who are having surgery to remove a stomach cancer and research has also suggested nerves may have a role in prostate cancer too but Wang acknowledged that there is a long way to go before this could be considered a treatment.

Cancer Research UK said it was early days and it is unclear whether the injections could help save lives.

“With everything new in cancer, even if it looks great, when you start to roll it out to patients it always seems cancer is smarter than we are,” Wang added. “Tumours have the ability to out-evolve any single agent, knocking one leg of a stool is probably not going to topple it.”
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Hadi Teherani-designed alpine nature spa opens at Hotel Krallerhof in Austria
Austria’s five-star alpine wellness retreat Hotel Krallerhof has been updated with a new nature- centric glass-fronted spa, Atmosphere by Krallerhof.
Wellness gets wild as JW Marriott safari retreat opens in Masai Mara National Reserve
JW Marriott has branched into the luxury safari segment with a wellness-forward retreat property in one of Africa's most renowned wildlife and wilderness conservation regions.
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Global online architecture platform Architizer has spotlighted innovative spa and wellness architecture concepts around the world as part of its 11th Annual Architizer A+Awards.
Wellbeing strategist Dr Glenda Rivoallan to keynote Spa Life UK 2023
Industry event Spa Life UK is back for 2023 from 2-4 July at the De Vere Cotswold Water Park Hotel.
Kelleye Martin named spa director of The Houstonian’s Trellis Spa
Iconic Texas hotel and wellness destination Texas The Houstonian Hotel, Club & Spa has announced the appointment of Kelleye Martin as the new director of its Trellis Spa.
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