28-29 Jul 2024
Southern Sun Rosebank,
Johannesburg,
South Africa
|
03-05 Sep 2024
IMPACT Exhibition Center,
Bangkok,
Thailand
|
03-08 Sep 2024
Cruise London, Amsterdam, Zeebrugge,
United States
|
08-10 Sep 2024
Wyndham® Lake Buena Vista Disney Springs™ Resort,
Lake Buena Vista,
United States
|
10-12 Sep 2024
St Moritz Hotel & Spa,
Wadebridge,
United Kingdom
|
15-18 Sep 2024
Wigwam,
Phoenix,
United States
|
18 Sep 2024
Chesford Grange Hotel,
Kenilworth,
United Kingdom
|
19-19 Sep 2024
The Salil Hotel Riverside - Bangkok,
Bangkok 10120,
Thailand
|
|
|
![](https://www.spaopportunities.com/images/trans.gif) |
Harvard scientists report breakthrough in how cells age and how to reverse the process |
|
By Katie Barnes 30 Mar 2023 |
It's easier to control epigenetic processes rather than reverse DNA mutations Credit: Shutterstock/Shurkin_son
|
A 13-year study by researchers at Harvard University has shown for the first time that the modification of gene expression can lead to cell ageing.
For years, mainstream thinking in scientific circles has been that ageing is caused by mutations in genetic code which causes cells to malfunction and die, however, this new study, published in the journal Cell, suggests that it’s the way DNA is governed that drives ageing.
In layman’s terms, the researchers are suggesting that ageing doesn’t mean cells are damaged and incapable of behaving like young cells, but rather that something has got lost in translation in their genetic make-up.
So, in theory, if we use epigenetic interventions to get cells back on the right path, they can ‘remember’ how to be young and fully functioning again – effectively reversing the ageing process.
Main experiment In the main experiment, scientists at Harvard mimicked breaks in chromosomes that cells experience every day in response to things such as breathing, exposure to sunlight and contact with certain chemicals.
They ensured these breaks did not occur in the coding regions of the DNA so mutations were prevented from occurring over time. The team noticed that the epigenome grew disorganised leading to more aged looks and behaviour.
Next, they delivered gene therapy to reverse the changes and found the organs and tissues had resumed their youthful state.
“It’s like rebooting a malfunctioning computer,” says the paper’s senior author David Sinclair, explaining that the therapy “led cells to restore the epigenetic information they had when they were young”.
A different view Co-first author Jae-Hyun Yang adds: “We expect the findings will transform the way we view the process of ageing and the way we approach the treatment of diseases associated with ageing.”
This is because it’s easier to manipulate the molecules that control epigenetic processes rather than to reverse DNA mutations. Such interventions could include injecting stem cells to “help rewind mature cells”, for example, or using drugs.
Sinclair hopes the work inspires other scientists to study how to control ageing to prevent and eliminate age-related conditions such as frailty, cardiovascular disease and Type 2 diabetes.
The ultimate goal, he concludes, would be to address the root causes of ageing to help people live healthier lives for longer.
|
|
News |
1 to 12 of 8769 news stories |
|
![](https://www.spaopportunities.com/images/trans.gif) |
25 Jul 2024
Retreat brand TheLifeCo Well-being will make its Caribbean debut in Gros-Islet, Saint Lucia, in 2025, as part of the Caribbean Jewel Seven Wonders project (CJSW). Since 2005, TheLifeCo has hosted retreat programmes focused on nutrition, ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
24 Jul 2024
Global online architecture platform Architizer has highlighted some of the world’s most innovative spa and wellness architecture concepts as part of its 12th Annual Architizer A+Awards. Split into 126 categories, the awards celebrate the work ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
24 Jul 2024
Billingehus, a tranquil Swedish countryside retreat, has unveiled its new 2,000sq m spa and announced new plans for additional upgrades by 2025. Situated between Gothenburg and Stockholm, the hotel and its new wellness facility are ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
23 Jul 2024
Bavarian destination spa and hotel Schloss Elmau is looking to celebrate the joy of dance by becoming the first wellness destination in the world to offer retreats focused on the Gaga intuitive movement practice. Gaga, ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
23 Jul 2024
Fitness-focused hospitality brand and management company Equinox Hotels has announced plans to open a modern new resort on the coast of the Gulf of Aqaba in northwest Saudi Arabia. The venture is part of the ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
22 Jul 2024
Plans have been unveiled for La Maviglia, a new luxury resort and expansive medi-spa set to open in Italy's Puglia region, renowned for its Primitivo wine, in 2027. Spanning 202 hectares of lush olive orchard ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
19 Jul 2024
Auberge Resorts Collection will launch its first UK property and destination spa in Mayfair, London, in 2025, following a deal with UK-based global private investment group Reuben Brothers. The 102-room hotel – called Cambridge House, ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
19 Jul 2024
A large new mineral springs destination has launched in Texas, inspired by some of the world’s most famous hot springs – such as Jordan’s Dead Sea, Iceland’s Blue Lagoon and Mexico’s Grutas Tolantongo. Located at ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
18 Jul 2024
A thought-provoking, US national probability study, The WELLSurvey™, has revealed that the majority of Americans now include several health and wellness practices in their everyday lives. They also view the concepts of 'wellness' and 'wellbeing' ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
18 Jul 2024
US integrative wellness brand The Well has named Ariella Willoughby as its new VP of operations, aiming to drive significant growth and operational success across its current and future locations worldwide. The Well, which launched ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
16 Jul 2024
Middleton Enterprises, a UK-based family investment office, has committed £1.6 million (US$2.1 million, €1.9 million) in funding to the Light Centre – a network of medical, therapeutic and wellbeing centres with four locations in London. ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
![](https://www.spaopportunities.com/images/trans.gif) |
15 Jul 2024
Rianna Riego, a seasoned professional in the wellness and spa industry, has been appointed director of global business development at Seed to Skin Tuscany, a premier Italian botanical skincare and spa brand. Riego brings more ... More
|
![](http://www.attractionsmanagement.com/images/trans.gif) |
|
|
![](https://www.spaopportunities.com/images/trans.gif) |
Spa Bureau |
The company Spa Bureau was established in 2009 by Inna Sidorova. The team has over 15 years’
[more] |
|
|
![](https://www.leisureopportunities.co.uk/images/dir/537258_410817.png) |
|